Problem Hypertension, age 60-79
Format -
Treatment Nifedipine
Control Placebo
Population 1632
Inclusion criteria -
Exclusion criteria -
Follow-up 36 months, mean 30 months
Primary endpoint Stroke, severe arrhythmia
Secondary endpoint(s) Blood pressure
Details .
Brief summary:
PAPER: Shanghai trial of nifedipine in the elderly (STONE).
Date 1 Oct 1996
Journal J Hypertens 1996;14:1237-45
Information -Significant reduction in strokes and severe arrhythmia
-BP reduced for nifedipine and placebo, greater benefit from nifedipine
-Increased benefit with longer treatment duration