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ECASS TRIAL |
|
|---|---|
| Problem | Acute ischaemic stroke |
| Format | - |
| Treatment | rt-PA |
| Control | Placebo |
| Population | 620 patients |
| Inclusion criteria | - |
| Exclusion criteria | - |
| Follow-up | 90 days |
| Primary endpoint | Barthel Index (BI) and modified Rankin Scale (RS) at 90 days |
| Secondary endpoint(s) | combined BI and RS, Scandinavian Stroke Scale (SSS) at 90 days, and 30-day mortality |
| Details | Treatment within 6 hours |
| Brief summary: | |
| PAPER: Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS) | |
|---|---|
| Date | 4 Oct 1995 |
| Journal | JAMA. 1995 Oct 4;274(13):1017-25. |
| Information | rt-PA given within 6 hours Improvement in some functional measures and neuro. outcome -In subgroup of patients with moderate-severe neuro -& without extended infarct on CT Therefore necessary to be able to identify this subgroup - difficult |