Problem HTN (SBP <160; DBP 80-95 mmHg)
Format Multicenter, non-blind, parallel-group, randomized, controlled trial
Treatment Diet modification
Control -
Population 459 patients
Inclusion criteria Aged 22 or over
Mean SBP <160mmHg
Mean DBP 80-95mmHg
Exclusion criteria Use of medications that affect BP
Poorly controlled DM
Cardiovascular event within 6 months
Chronic diseases that may interfere with study participation
Pregnany or lactation
BMI >35 kg/m2
Unwilling to stop vitamins, mineral supplements, or antacids containing Mg or Ca
>14 alcoholic drinks per week
Follow-up 8 week intervention phase (following run-in)
Primary endpoint Changes in resting DBP
Secondary endpoint(s) Changes in resting SBP
Changes in ambulatory DBP
Changes in ambulatory SBP
Details -
Brief summary: Small but significant BP reductions from diet control
PAPER: A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group.
Date 17 Apr 1997
Journal N Engl J Med. 1997 Apr 17;336(16):1117-24.
Information Patients assigned to 8 weeks of either
-'Typical American' control diet
-Diet rich in fruits and vegetables
-\combination\" diet rich in fruits, vegetables, low-fat dairy products, with reduced saturated and total fat
Reduced sodium intake and alcohol consumption recommended for all patients

Fruit and veg. diet reduced BP by 2.8/1.1 mmHg vs. control
Combined diet reduced by by BP by 5.5/3.0 mmHg vs. control
-Results seen within 2 weeks
-Continued until end of intervention (6 weeks)